EPH Receptor A2 anticorps (AA 296-323)

N° du produit ABIN3030814

Cet anticorps Lapin Polyclonal détecte spécifiquement EPH Receptor A2 dans WB et ELISA. Il présente une réactivité envers Souris.

Aperçu rapide pour EPH Receptor A2 anticorps (AA 296-323) (ABIN3030814)

Antigène: EPH Receptor A2 (EPHA2)

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor A2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-EPH Receptor A2 anticorps

Épitope: AA 296-323

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 296-323 from the mouse protein was used as the immunogen for this Epha2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Epha2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Epha2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur EPH Receptor A2

Antigène: EPH Receptor A2 (EPHA2)

Autre désignation: Epha2

Sujet: Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A3, -A4 and -A5. Induces apoptosis in a TP53/p53-independent, caspase-8-dependent manner (By similarity). Plays an important role in angiogenesis and tumor neovascularization. The recruitement of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues. May be involved in cell-cell interactions guiding early hindbrain development.

UniProt: Q03145

Pathways: Signalisation RTK